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It is not approved for human or veterinary use and is not intended for clinical administration, therapeutic application, diagnostic procedures, or consumption of any kind

Researchers have proposed several mechanisms, including direct effects on gene transcription factors and indirect influences through cellular signaling cascades that regulate telomerase activity

N Engl J Med 314(23):14941497 Rocha JF, Vaz-Da-Silva M, Nunes T, Igreja B, Loureiro AI, Bonifcio MJ, Wright LC, Falco A, Almeida L, Soares-Da-Silva P (2012) Single-dose tolerability, pharmacokinetics, and pharmacodynamics of etamicastat (BIA 5453), a new dopamine -hydroxylase inhibitor, in healthy subjects