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For cardiovascular risk (Wegovy): Established cardiovascular disease prior MI, prior stroke, or symptomatic PAD plus BMI 27

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[GLP-1 receptor expression in rat major salivary glands and the effects of bilateral maxillary molar extraction on its expression]

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Taken together, this evidence suggests that the heterogeneity of studies models and the interaction of many adaptive mechanisms might explain the variable results in the recent studies concerning the influence of SGLT2-i treatment on the RAAS, although an activation of intrarenal RAS in chronic treated patients has been excluded (42)