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It carries a boxed warning regarding the risk of thyroid C-cell tumors observed in rodent studies and should not be used by individuals with a personal or family history of medullary thyroid carcinoma or Multiple Endocrine Neoplasia syndrome type 2, during pregnancy, or where otherwise contraindicated

doi:10.1016/j.celrep.2023.113587 6

Brand-name tirzepatide (Mounjaro/Zepbound) can be expensive