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melanogaster are easy and cheap to perform, and existing or specially produced fly lines with deleted regulatory/effector systems may be tested to provide further clues as to the biological action and side-effects of the candidate compound

Microscopy, digital imaging and morphometry Samples were digitalized by Olympus FluoView 1000 confocal microscope (Olympus Europe, Hamburg, Germany) in analogue mode with sequential scanning

Furthermore, researchers noted that the use of combination therapy, consisting of doxorubicin and Navitoclax (responsible for removing aging cells), led to only a 20% decrease in the running activity of p16-3MR mice, compared to the therapy with doxorubicin alone, where this coefficient reached 50% [60]