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All primer sequences are listed in Supplementary Table 1

Dihydroxyacetone, the active browning ingredient in sunless tanning lotions, induces DNA damage, cell-cycle block and apoptosis in cultured HaCaT keratinocytes

Clinical Evidence for Semaglutide and Abdominal Fat Loss The SELECT trial and multiple real-world cohort studies documented that semaglutide reduces visceral adipose tissue volume by 15-35% depending on baseline body composition and duration of therapy

It emphasizes how age-related declines in melatonin secretion and signaling contribute to circadian dampening, sleep fragmentation, increased oxidative stress, and chronic low-grade inflammation