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Instead, cellular uptake is expected to occur primarily through clathrin-mediated endocytosis and macropinocytosis, facilitated by its small size

It is thought to be the first death officially linked to the drug in the UK Ms McGowan worked as a nurse at University Hospital Monklands in Airdrie for more than 30 years

Some preliminary studies suggest allulose might interact with sweet taste receptors (T1R2/T1R3) or other nutrient-sensing mechanisms on enteroendocrine cells

While formal published trials specific to GLP-1 addiction India are limited, practitioners are looking to global studies and adapting insights for Indian patients

Ethics declarations Competing interests RJK, SBG, RS, PA, PP, SD, PS, SA and JC declare no conflicts of interest related to this study