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The Cochrane Collaboration Risk-of-Bias tool was used for quality assessment of the RCTs [18], including sequence generation, allocation concealment, blinding, incomplete outcome data, and selective outcome reporting

Another oral GLP-1 RA product, ORMD-0901, developed by Oramed, was tested in Phase 2 clinical trials [207]

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This has occurred partly due to the very success of these drugs, and the lack of availability may result in patients being unable to persist with the drug

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