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Activation of these receptors modulates dopamine release, the neurotransmitter central to reward processing and addictive behaviors, potentially reducing cravings for alcohol and other substances

They must also have at least four other health problems linked to obesity, such as type 2 diabetes, high blood pressure, heart disease, high cholesterol and obstructive sleep apnoea

While the test doesn't directly predict vertigo, it identifies individuals likely to experience intense early side effects, allowing clinicians to design slower, gentler dosing schedules that minimize dizziness

Packing your injection pen in your carry-on bag is the safest option because it keeps the medication under your direct supervision and away from cargo hold temperature extremes that could damage the compound

Patients were randomized in a 2:1 ratio to either WEGOVY or placebo