glp 1 being discontinued ‼️GLP 1 saga update 🚨, Now that the compounded GLP 1 Most Patients Discontinue GLP-1 Drugs

Comparative effects of intragastric and intraduodenal administration of quinine on the plasma glucose response to a mixed-nutrient drink in healthy men: relations with glucoregulatory hormones and gastric emptying

The newer generation medications are once weekly, so the half-lives are decently long, and it takes a full 4 to 8 weeks for the molecule to be completely outside of the system

If Foundayo's clinical outcomes hold up in real-world use (the Phase 3 ATTAIN-1 trial showed 11.2% mean weight loss at 72 weeks on the 36 mg dose, or 12.4% among participants who stayed on treatment), it could become the go-to affordable GLP-1 option and put downward pressure on Wegovy and Zepbound pricing

KEY OBSERVATIONS Textbook cold-chain handling featured ice packs, dry ice, insulated packaging, and a clear barrier between the cold materials and medication

doi: 10.1128/mSystems.00130-17 55 LouisPYoungPHoltropGFlintHJ