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Nature Medicine , 18(6), 843-849

Insurance coverage for Zepbound (the weight management indication) has been inconsistent, with many commercial plans applying prior authorisation requirements and some government programmes excluding coverage for obesity medications entirely

These categories differ in the magnitude and direction of receptor activation, enabling tailored therapeutic applications depending on disease mechanisms and required biological responses

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Aunque son eficaces en el tratamiento de la obesidad y los trastornos metablicos, los tratamientos con agonistas de los receptores GLP-1 y GIP pueden tener efectos secundarios que son una causa frecuente de interrupcin del tratamiento