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Adler, V

Body composition, IGF-I and IGFBP-3 concentrations as outcome measures in severely GH-deficient (GHD) patients after childhood GH treatment: a comparison with adult onset GHD patients

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Results showed: HbA1c reduction of up to 2.02% at the 12 mg dose Body weight reduction of up to 16.9% at 36 weeks Over 70% of participants achieved HbA1c below 5.7% (non-diabetic range) Significant reductions in liver fat content (measured by MRI), with some participants achieving complete resolution of hepatic steatosis Liver Fat Reduction One of the most clinically significant secondary findings from retatrutide trials has been its effect on liver fat