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TB-500 and Neurological Recovery Research In a rat embolic stroke model, administration of T4 at 24 hours after middle cerebral artery occlusion and every 3 days for 4 additional doses produced significant improvement in functional neurological outcome with evidence of axonal remodelling at the ischaemic boundary, increased oligodendrocyte precursor cells in the SVZ, striatum, and corpus callosum, and increased mature oligodendrocytes suggesting a mechanism involving axonal remodelling rather than direct neuroprotection
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doi: 10.3389/fbioe.2021.643722 Summary Keywords antifungal, alginate oligosaccharide, nystatin, Candida spp., biofilm Citation Powell LC, Adams JYM, Quoraishi S, Py C, Oger A, Gazze SA, Francis LW, von Ruhland C, Owens D, Rye PD, Hill KE, Pritchard MF and Thomas DW (2023) Alginate oligosaccharides enhance the antifungal activity of nystatin against candidal biofilms
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