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The most significant concern is reduced drug absorption
Am J Chin Med 31:885895 Chen X, Shen X, Guan Sh, Liu Y, Song N, Song W, Jin H (2025) Mechanisms of c-Fos regulation of mTOR signaling via ER/ in abnormal lipid metabolism of granulosa cells in PCOS
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On the day of the experiment (57 d after surgery), freely moving rats received AEF0117 or vehicle, and the microdialysis probe was implanted into the guide cannula that was then perfused with artificial cerebrospinal fluid
The least-squares mean percentage change in body weight at 24 weeks in the retatrutide groups was 7.2% in the 1-mg group, 12.9% in the combined 4-mg group, 17.3% in the combined 8-mg group, and 17.5% in the 12-mg group, as compared with 1.6% in the placebo group
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