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In addition to its benefits in diabetes and cancer, metformin has been shown to promote weight loss and protect against cardiovascular disease, Alzheimer disease, and non-alcoholic fatty liver disease (Forouzandeh 2014

Our investigation identifies new potentially druggable locations in the receptor, expanding the existing repertoire of functionally relevant sites for the rational design of novel GLP-1R allosteric modulators based on the modulation of receptor-cholesterol interactions

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A 68 year old female presented to the ED with epigastric abdominal tenderness for 2 days and 3 episodes of non-bloody emesis of undigested food after eating breakfast

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