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Cardiovascular health GLP-1s may help reduce risk for major adverse cardiovascular events, stroke, death and myocardial infarction in older adults with type 2 diabetes

The primary mechanisms of action include: Enhancing insulin secretion from pancreatic beta cells in a glucose-dependent manner, which helps lower blood glucose levels without causing hypoglycaemia when used alone Suppressing glucagon release from pancreatic alpha cells, reducing hepatic glucose production Slowing gastric emptying , which prolongs the feeling of fullness after meals Acting on appetite centres in the brain , particularly the hypothalamus, to reduce hunger and food intake GLP-1 receptor agonists are typically administered via subcutaneous injection, with dosing frequencies ranging from once daily to once weekly depending on the specific medication, though oral semaglutide (Rybelsus) is also available

Pharmacogn Res 6(4):274 Ekenze CJ et al (2022) Explorative in vitro evaluation of the inhibitory effect of Vitellaria paradoxa seed oil extract on staphylococcal conjunctivitis

These observations underline the potency of NFT as a pharmacological Nrf2 activator

Q: What lifestyle changes should I make while on these treatments