Whilst mild gastrointestinal symptoms are common and often self-limiting, certain warning signs require prompt medical evaluation
A joint advisory from four major medical organizations identified specific nutrients of concern for people on GLP-1 and GIP receptor agonists: Vitamin D: Already deficient in roughly 40% of adults before starting tirzepatide, critical for bone density, immune function , and mood regulation Vitamin B12: Essential for nerve function and red blood cell production, deficiency causes fatigue and cognitive fog Iron: Particularly concerning for menstruating women, deficiency leads to anemia and severe fatigue Calcium: Bone density protection becomes critical during rapid weight loss Magnesium: Involved in over 300 enzymatic processes, deficiency causes muscle cramps, poor sleep, and muscle pain Zinc: Supports immune function, wound healing, and hair health, deficiency contributes to hair loss on GLP-1 medications Potassium: Electrolyte balance, especially important if you experience vomiting or diarrhea Choline: Liver health and brain function, found primarily in eggs and liver Signs you are becoming deficient Watch for these warning signs
Note: Always confirm that your fridge has a temperature of 2C - 8C
What results have been observed in clinical trials for tirzepatide
This matters for two reasons
