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Effective topical GSH 25 may be useful for dermatologists treating hyperpigmentation, but it is worth noting that GSH as a thiol interacts with metalloid complexes that render it ineffective

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When the HPA axis is activated, CRF is released from the paraventricular nucleus(PVN) into the portal circulation, stimulating the pituitary to produce and release adrenocorticotropic hormone (ACTH)

27 Vitamin C acts as a ROS scavenger and thus can rescue vitamin E, which is anchored in the cell membrane and prevents lipid peroxidation

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