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However, the intake of dietary supplements containing creatine augments both serum creatine concentration and muscle creatine concentration, as the rates of endogenous creatine synthesis (1 g/day) or ingestion through foods (12 g/day) are very limited in comparison to the doses habitually ingested through dietary supplements (from 5 to 20 g/day depending on the loading protocol)

doi: 10.1016/j.jacc.2003.12.049 112

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This VAS paper is today a classic methods paper in this field [3] and has been cited 2,382 times