Semaglutide The active ingredient in Wegovy and Ozempic The mean change in body weight from baseline to week 68 was -14.9% in the semaglutide group, as compared with -2.4% with placebo. STEP 1, Wilding JPH et al., NEJM 2021;384:989-1002 Tirzepatide The active ingredient in Mounjaro and Zepbound At 72 weeks, the mean percentage change in weight was -20.9% with 15 mg of tirzepatide, as compared with -3.1% with placebo. SURMOUNT-1, Jastreboff AM et al., NEJM 2022;387:205-216 These figures are trial averages for the branded formulations
Prices vary based on medication dose, program duration, and individual treatment plan
If you win the appeal, the insurer will cover Zepbound
Most people did fine on semaglutide
GIP Action: Enhances GLP-1s insulin-stimulating effects, reduces fat storage in adipose tissue, and improves the bodys sensitivity to GLP-1 signaling, making the combination significantly more powerful than either hormone alone