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Throughout this review, mechanistic insights derived from cellular and animal models are discussed separately from translational observations and human clinical or observational data

Cellular senescence refers to a molecular and tissue-level mechanism involving irreversible cell-cycle arrest, altered metabolic activity, and the acquisition of a senescence-associated secretory phenotype (SASP), which can influence tissue function and intercellular communication

02 Mechanism: How It Works GHK-Cu modulates gene expression

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