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Add-on to 1-3 oral anti-hyperglycemic agents (metformin, sulfonylurea, or SGLT-2 inhibitor) SURPASS-4 (NCT03730662) was a 104-week open-label trial (52-week primary endpoint) that randomized 2002 adult patients with type 2 diabetes mellitus with increased cardiovascular risk to subcutaneous MOUNJARO 5 mg, MOUNJARO 10 mg, MOUNJARO 15 mg once weekly, or insulin glargine 100 units/mL once daily (1:1:1:3 ratio) on a background of metformin (95%) and/or sulfonylureas (54%) and/or SGLT2 inhibitors (25%)

Could be copper just falling out of the, the complex of the ghk

however, compounded drugs themselves are not FDA-approved for safety or effectiveness

Concentrations above 4% have not demonstrated proportionally greater benefits in published literature

The typical dosage ranges from 250 to 500 micrograms per day, but this can vary based on individual needs