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1 Animal studies The Wegovy SmPC reports that in pregnant rats given semaglutide, the developing pups showed signs of harm at doses lower than those used to treat obesity in humans

In these cases, a clinician will prescribe a particular dose that is below the FDA-approved amount

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Additionally, because many people with diabetes or who are overweight may control their condition with diet, other medications and therapies, or choose to not seek treatment, not all people who meet these clinical criteria would use GLP-1 drugs

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