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The Hallmarks of Aging

Cook explains Noom is staying up-to-date with industry-wide changes, and plans to evolve with it

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10.1111/1756-185X.13457 94

For breeding, male VE-Cadherin-Cre ERT2 mice were crossed with female Igf1r f/f mice to generate VE-Cadherin-Cre ERT2 /Igf1r + / males, which were subsequently bred with Igf1r f/f females to establish the VE-Cadherin-Cre ERT2 /IGF1R homozygous floxed founder colony, following our previously described protocol [17, 45]