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doi: 10.1056/nejmoa2511774

The FDA cleared orforglipron for chronic weight management in adults with obesity, or overweight with at least one weight-related comorbidity, based on the ATTAIN clinical program which showed placebo-adjusted weight loss of 7.5% to 11.2% in non-diabetics (ATTAIN-1) and 5.1% to 9.6% in diabetics at different doses, along with the expected glycaemic benefits (ATTAIN-2)

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Proactive risk mitigation strategies can minimize gastroparesis-related complications in patients prescribed GLP-1 receptor agonists

If you're on a similar path, remember to focus on consistency, patience, and kindness towards yourself