Sermorelin and Tesamorelin have extremely short half-lives of roughly 1126 minutes because they are minimally modified growth hormone-releasing hormone analogs that are rapidly cleaved by dipeptidyl peptidase-4 and other serum proteases
15:30071 Topically applied GHK as an anti-wrinkle peptide: advantages, problems and prospective Pickart L, Vasquez-Soltero JM, Margolina A., BioMed Research International , 2015
Thymosin beta-4 adds actin-regulatory functions essential for cellular motility and wound healing, and KPV contributes anti-inflammatory activity derived from melanocortin signaling pathways
El Eid L, Reynolds CA, Tomas A, et al
When combined with insulin or sulfonylureas, dose adjustments of these medications are frequently necessary to reduce the risk of hypoglycemia, as the glucose-lowering effects may be additive