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Research revealed that perivascular pathways and brain parenchyma astrocytes facilitate exchange between cerebrospinal and interstitial fluids while removing metabolic waste (Silva et al

The systems biology graphical notation: current status and applications in systems medicine

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81 It is important to note that, paradoxically, some of the drugs used to treat tinnitus can also cause tinnitus, and none are currently recommended as primary therapies for tinnitus

this may be an advantage for preterm infants during the first days of life because of their immature neurological system [133]