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(b) Is it appropriate to completely disregard the universally accepted concept of RISK-BENEFIT RATIO assessment

For type 2 diabetes management, the medication may be needed long-term as diabetes is a chronic condition requiring ongoing treatment, though some patients may be able to reduce or discontinue medication if significant weight loss and lifestyle modifications lead to remission of their diabetes

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In addition, these studies suggested that these peptides may modulate food intake, cardiac tone, and sleep through apparently specific receptor agonistic action

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