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Frequencies vary across the available data sources and are best read in the SmPC for tirzepatide on the electronic Medicines Compendium

Many people successfully stop treatment after reaching their weight-loss goal, though some weight regain (typically 25-50% of lost weight) may occur within 1-2 years if lifestyle habits don't remain consistent

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4) significant decrease of IL-5 levels in ALS patients at the first visit was not present at the second visit