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A substance or method may still be prohibited if: it is not approved for human therapeutic use by any regulatory authority (e.g

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To achieve this, they used alginate/chitosan-based hydrogels and cross-linked with tissue surface to achieve tissue adhesion, whereas the use of polysaccharide further promoted the tissue adhesion, thus resulting in good biocompatibility and enhanced antibacterial activity, which can be used in tissue engineering [174]