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/EBP homologous protein contributes to cytokine-induced pro-inflammatory responses and apoptosis in beta-cells

Recent studies have revealed an autoregulatory mechanism whereby mitochondrial GSH (mtGSH) homeostasis is controlled through a feedback loop involving solute carrier family 25 member 39 (SLC25A39) transporter and mitochondrial protease AFG3 like matrix AAA peptidase subunit 2 (AFG3L2), coupling GSH levels to iron-sulfur cluster biogenesis 16,17

It can also support a balanced immune system

2024 May 17 [cited 2025 Oct 21];27(5)

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