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Rapid acidification is required to prevent GSH auto-oxidation, GSH and GSSG degradation, as well as to precipitate proteins that interfere with analysis

2 The canonical Wnt pathway, also known as the Wnt/-catenin pathway, involves the nuclear translocation of -catenin and activation of target genes via TCF/LEF transcription factors

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7 In 1993, a German laboratory confirmed what Engs paper had implied: exendin-4 was not merely structurally similar to GLP-1 it was a high-potency agonist at the human GLP-1 receptor, stimulating the same cAMP signaling cascade in insulin-secreting beta cells and amplifying glucose-induced insulin secretion