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Weight loss with Tesofensine was primarily fat mass, with a notable preservation of lean mass as assessed by DEXA. Astrup et al., The Lancet May Improve Training Drive and Mood Elevated dopamine and norepinephrine levels can enhance motivation , focus , and mental resilience during challenging cutting phases

Additionally, controlling hunger and increasing energy can positively affect mental well-being, contributing to a holistic approach to health

For sustained weight loss, pair interventions: nutrition, behavior change, progressive activity, and, where suitable, medications or supplements backed by trials

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