GLP-1 receptor agonists, like Ozempic, Wegovy, Mounjaro, and Zepbound, initially developed for diabetes management, show promising potential in treating psoriasis and psoriatic arthritis (PsA)
Owing to their high intracellular abundance, they also serve as indicators of compromised cellular integrity: once released extracellularly, HSP70s act as damage-associated molecular patterns (DAMPs), triggering immune responses through receptors such as the toll-like receptors TLR2 and TLR4 (Theivanthiran et al., 2022
Prog Neuropsychopharmacol Biol Psychiatry 2006;30:103942
If you are curious about how GLP-1 drops work in general, the concept relies on bypassing the digestive system to improve bioavailability, though the evidence for this approach with supplement ingredients remains limited
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