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LDL cholesterol (the 'bad' cholesterol linked to plaque buildup) also declined, though the effect was more modest than triglyceride reduction

As a secondary effect, release of the neurotransmitter acetylcholine was reduced, and the authors concluded that this cell model might allow further investigations on neuronal functions in Fabry disease

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In addition to the APC mutation, an AXIN2 mutation is also common in CRC

[12] At even higher pH, the other carboxylic acid group loses its proton and the acid exists almost entirely as the glutamate anion OOCCH(NH + 3 )(CH 2 ) 2 COO , with a single negative charge overall