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Sawka AM, Fatourechi V, Boeve BF, Mokri B
In examining the GHSR1a-MC3R dimer, Schellekens et al
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Features Afamelanotide is a potent, linear synthetic analog of the naturally occurring peptide hormone -melanocyte-stimulating hormone (-MSH).Modified to have a stronger binding affinity to melanocortin- 1 receptor (MC1R) and a smaller disassociation constant, afamelanotide has a longer half-life and subsequently exerts longer pharmacologic activity than its parent hormone