If you have documented semaglutide failure, your provider can use this as leverage for insurance approval of tirzepatide coverage
[DOI] [PubMed] [Google Scholar] [203].Holst JJ, Madsbad S, Semaglutide seems to be more effective the other GLP-1Ras, Ann Transl Med, 5 (2017) 505
But drug manufacturers do not have much incentive to make such a deal because demand is already enormous for GLP-1s, Klebanoff said
Current studies suggest that peripherally administered GLP-1RA has low concentrations in the cerebrospinal fluid, and higher doses or improved delivery systems (e.g., nanoparticles, liposome encapsulation) may be needed to increase brain exposure
Like avocados, nuts are high in fiber