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GSH levels were also found to be decreased in the frontal cortex of patients with AD, and the GSH reductions in these regions were correlated with the decline in cognitive functions [100]

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NAD + , the co-enzyme of reduced NADPH, plays a critical role in redox reactions, energy metabolism, mitochondrial function, calcium homeostasis, DNA repair, and SIRT1 gene expression (Yaku et al., 2018

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16 The average IVD height was calculated by averaging the measurements obtained from the anterior, middle, and posterior portions of the IVD and dividing that average by the average of adjacent vertebral body heights

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