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It's unknown whether this occurs in humans, but the medications should not be used if you or a family member has a history of medullary thyroid carcinoma or Multiple Endocrine Neoplasia syndrome type 2

36 Finally, a cross-sectional study also demonstrated adverse effects of GLP-1 agonists, with patients on exenatide reporting higher PHQ-9 scores (9.70 4.92 vs 6.70 4.66

The authors hypothesized that the drug lowers migraine frequency by reducing intracranial pressure

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