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Biologic agents targeting specific inflammatory pathwaysincluding TNF- inhibitors (adalimumab, etanercept), IL-6 inhibitors (tocilizumab), T-cell costimulation modulators (abatacept), and B-cell depleting agents (rituximab)provide additional options for patients with inadequate response to conventional therapy

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[DOI] [PMC free article] [PubMed] [Google Scholar] 175.Kalra B, Gupta Y, Singla R, Kalra S

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At first glance, this seems paradoxical: glucagon is the hormone of energy mobilization, the opposite of insulin