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10.1371/journal.pone.0146797 Summary Keywords autism, folinic Acid, glutathione, methylation, methylcobalamin, oxidative stress, tetrahydrobiopterin Citation Delhey LM, Tippett M, Rose S, Bennuri SC, Slattery JC, Melnyk S, James SJ and Frye RE (2018) Comparison of Treatment for Metabolic Disorders Associated with Autism:Reanalysis of Three Clinical Trials

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108 Released Cyt c and apoptotic protease activating factor-1 (Apaf-1) form a multimeric complex, then the caspase recruitment domain (CARD) at the amino terminus of Apaf-1 recruits the cytoplasmic caspase-9 precursor to form a new complex

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