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Multifaceted changes in synaptic composition and astrocytic involvement in a mouse model of fragile X syndrome

Indeed, synaptic activity driven functional changes of inhibitory neurotransmission are accompanied by modifications in the structure of GABAergic synapses with two major consequences: alteration of synaptic size and morphology and formation and elimination of inhibitory contacts (Figure 1)

The Journal of clinical endocrinology and metabolism, 89(5), 22902300

A dimer of two cysteines linked by disulfide bridge

The impact of NSAIDs on intestinal permeability is reinforced by the estimated 6080% of individuals using these drugs who display a disrupted gut barrier