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However, these improvements were not observed with liraglutide

In poorly controlled diabetes, excess glucose in the blood is filtered into urine (glycosuria), drawing water with it through osmotic diuresisa process that causes frequent urination

The Journal of Sexual Medicine, 9 (8), 2057-2065

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Ozempic (semaglutide) and spironolactone are both common prescriptions, but their combination requires careful attention because both medications affect your body's fluid balance and electrolyte levels in different ways