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Phytosomes are well suited for oral and topical administration and preparation techniques such as solvent evaporation, rotary evaporation, and lyophilization are commonly employed to bind plant extracts with phospholipids for improved pharmacokinetic properties and targeted therapeutic effects [89, 90]

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It is plausible that betaine supplementation promotes athletic performance by maintaining cellular hydration and reducing homocysteine levels, thereby encouraging healthy cardiovascular function and blood flow [16]

Combination research should rest on a clear mechanistic rationale