The Arg3 substitution replaces one amino acid (arginine at position 3), making the compound less likely to bind to IGF-binding proteins that normally deactivate IGF-1 in the bloodstream
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Silymarin is extracted from the seeds and fruit of milk thistle ( Silybum marianum ), a plant rich in the flavonolignans silychristin, silydianin, and silybin, which are collectively known as the silymarin complex (Kohno 2002
It forms glutathione peroxidase , which is the cell's intracellular antioxidant defense against free oxygen radicals
By wrapping the glutathione molecule in this protective layer, we allow it to pass through the digestive system safely