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Peri-lesional injection requires precise anatomical knowledge and a higher technical skill level, and the marginal benefit over subcutaneous delivery is not clearly established

One study found that girls who regularly drink milk are 44% more likely to develop acne

Recently, an emerging safety signal has linked potent GLP-1RAs like semaglutide and tirzepatide to NAION

The oral berberine research - the closest relevant reference - has typically studied outcomes over 2 to 3-month periods to capture meaningful metabolic changes

It was also supported by National Key Research and Development Plan by the Ministry of Science and Technology in China (2017YFC1308602)