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Taken together, the convergence of ferritinophagy-derived labile iron and pathology-related mitophagy deficiency creates a hypersensitive state, heightening the induction of cell death by Erastin in EESCs

Upon treatment with 3-MA, LC3II/LC3I expression was down-regulated and p62 expression increased, indicating an inhibition of autophagy(Fig

Due to its ability to improve the hormonal profile and metabolic parameters of women with reproductive disorders, the administration of LC to patients with functional hypothalamic amenorrhea improved the course of the disease [103] and reduced cytokine production

To explore the T3 action in vivo, mice were rendered hypothyroid (MMI mice) by addition of 0.1% methimazole (M8506, Sigma) and 1% NaClO 4 (410241, Sigma) in their drinking water for 20 days as indicated 43

Consequently, the skin becomes more resistant to environmental damage