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Contraindicated in people with a history of liver or kidney disease, as it may put additional strain on these organs

Studies indicate that these medications can lower systolic blood pressure by approximately 2 mmHg

Characterization and measurement of dehydroepiandrosterone sulfate in rat brain

An important nuance: while the trials did not publish detailed BMI-stratified results in their primary papers, the data consistently shows that higher baseline BMI correlates with greater absolute weight loss in kilograms, while lower baseline BMI correlates with greater percentage weight loss

Potential Brain Health Benefits: Emerging research is exploring the role of GLP-1 medications in supporting brain health and reducing inflammation in the nervous system