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Some patients describe the feeling as barely noticeable, while others report a more pronounced sting lasting a few seconds

GLP-1Rs are also expressed in neurons, astrocytes, microglia and retinal cells [18, 19]

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In a clinical trial that included 183 patients with early-stage breast cancer who were to undergo treatment with taxane-based adjuvant chemotherapy, GM1 substantially reduced the occurrence of peripheral neuropathy after four cycles of chemotherapy