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Intravenous (IV) Glutathione provides direct delivery into the bloodstream, but requires ongoing clinic visits and may be less practical for long-term use

Therefore, we investigated the possible mechanism of GLP-1RA action on tumors based on the results of existing studies

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It is a synthetic biguanide, originally derived from a guanidine compound found in Galega officinalis , a medicinal plant historically used to alleviate diabetic symptoms as early as the 18th century ( Initially, metformin attracted limited clinical interest due to its relatively low potency and the need for high doses to achieve therapeutic effects

"The identity of glutathione S -transferase B with ligandin, a major binding protein of liver"