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Alternatively, some patients attempt discontinuation after reaching their goal, supported by intensive behavioral programs, registered dietitian coaching, and structured exercise protocols

If your current provider lacks knowledge about these options, consider consulting with menopause-trained clinicians on platforms such as Alloy, Midi Health, or Evernow

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15 Phase II trials targeting MASH have shown that treatment with SEMA 0.4 mg daily for 72 weeks resulted in more patients with liver fibrosis stage F2/F3 achieving improvement in MASH without progression of liver fibrosis (odds ratio = 6.87, 95% CI = 2.6017.63) compared to placebo